The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2009

Filed:

Mar. 17, 2004
Applicants:

Kenji Soejima, Kumamoto, JP;

Tomohiro Nakagaki, Kumamoto, JP;

Masanori Matsumoto, Nara, JP;

Yoshihiro Fujimura, Nara, JP;

Inventors:

Kenji Soejima, Kumamoto, JP;

Tomohiro Nakagaki, Kumamoto, JP;

Masanori Matsumoto, Nara, JP;

Yoshihiro Fujimura, Nara, JP;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/04 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides an epitope recognized by an antibody (hereinafter, also referred to as an anti-ADAMTS-13 antibody) against a cleaving protease (hereinafter, also referred to as ADAMTS-13) specific to von Willebrand factor (hereinafter, also referred to as vWF), and a polypeptide comprising the epitope region. The present invention also provides a polypeptide located in a region from position 449 to position 687 in an amino acid sequence composing the ADAMTS-13, which is recognized by the anti-ADAMTS-13 antibody, or a peptide fragment derived from the polypeptide.


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