The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2009
Filed:
Sep. 25, 2003
Kenji Soejima, Kumamoto, JP;
Noriko Mimura, Kumamoto, JP;
Hiroaki Maeda, Kumamoto, JP;
Chikateru Nozaki, Kumamoto, JP;
Takayoshi Hamamoto, Kumamoto, JP;
Tomohiro Nakagaki, Kumamoto, JP;
Kenji Soejima, Kumamoto, JP;
Noriko Mimura, Kumamoto, JP;
Hiroaki Maeda, Kumamoto, JP;
Chikateru Nozaki, Kumamoto, JP;
Takayoshi Hamamoto, Kumamoto, JP;
Tomohiro Nakagaki, Kumamoto, JP;
Abstract
It is intended to provide an antibody showing immunoreactivity selectively to ADAMTS-13 and applications of this antibody in epitope analysis or diagnosis of an ADAMTS-13 autoantibody-positive patient. Alternatively, it is intended to provide a process for producing and use of a modified ADAMTS-13 molecule partially deleted aiming at the application in pharmaceutical products. An antibody specific for ADAMTS-13 which can be obtained from a warm-blooded animal immunized and sensitized with a polypeptide containing a part or the whole of ADAMTS-13 amino acid sequence; a process for producing an antibody comprising a step of immunizing and sensitizing a warm-blooded animal with a polypeptide containing a part or the whole of ADAMTS-13 amino acid sequence; use of the above-described antibody including a method of detecting and purifying ADAMTS-13; and a modified ADAMTS-13 molecule partially deleted are provided.