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For the Inventor, By the Inventor

Carlsbad, CA, United States of America

Thomas W Bruice

This inventor holds 23 USPTO granted patents, primarily in Nucleotide Chemistry. Top assignees: Isis Pharmaceuticals, Inc., Genelabs Technologies, Inc., Biota Scientific Management Pty Ltd. Active years: 1994-2010.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Thomas W Bruice. Retrieved from https://idiyas.com/inventor/thomas-w-bruice

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Calculating rank
USPTO Granted Patents = 23

% Patents Active = 78.3

Average Co-Inventor Count = 4.2

ph-index = 13

Forward Citations = 845(Granted Patents)


Company Filing History:

goldMedal16 out of 1,035 
 
Isis Pharmaceuticals, Inc.
 patents
silverMedal4 out of 72 
 
Genelabs Technologies, Inc.
 patents
bronzeMedal2 out of 54 
 
Biota Scientific Management Pty Ltd
 patents
4. 1 out of 9 
 
Biota, Inc.
 patents

Years Active: 1994-2010

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Areas of Expertise:
Nucleotide Mimics
RNA Modulation
Gene Expression
Hepatitis C Treatment
Oligonucleotides
Molecular Switch
Nucleic Acid Ligands
Cross-Linked Oligonucleotides
Synthetic Unrandomization
RNA Activity Inhibition
Diagnostics
Therapeutics
23 patents (USPTO):Explore Patents
1. 7807653 - Nucleotide mimics and their prodrugs (2010-10-05),
2. 7598230 - Nucleotide mimics and their prodrugs (2009-10-06),
3. 7285658 - Nucleotide mimics and their prodrugs (2007-10-23),
4. 7189506 - DNA binding compound-mediated molecular switch system (2007-03-13),
5. 6838556 - Promoters for regulated gene expression (2005-01-04),
6. 6610663 - Compositions and methods for modulating RNA (2003-08-26),
7. 6423489 - Compositions and methods for treatment of Hepatitis C virus-associated diseases (2002-07-23),
8. 6420109 - Nucleic acid ligand interaction assays (2002-07-16),
9. 6391542 - Compositions and methods for treatment of Hepatitis C virus-associated diseases (2002-05-21),
10. 6368863 - Reagents and methods for modulating gene expression through RNA mimicry (2002-04-09),
11. 6358931 - Compositions and methods for modulating RNA (2002-03-19),
12. 6355428 - Nucleic acid ligand interaction assays (2002-03-12),
13. 6022691 - Determination of oligonucleotides for therapeutics, diagnostics and (2000-02-08),
14. 5874564 - Reagents and methods for modulating gene expression through RNA mimicry (1999-02-23),
15. 5866698 - Modulation of gene expression through interference with RNA secondary (1999-02-02),

Title: The Innovative Journey of Thomas W. Bruice

Introduction: Thomas W. Bruice, a distinguished inventor hailing from Carlsbad, CA, has made significant contributions to the field of innovation with his groundbreaking work.

Latest Patents: Thomas W. Bruice holds several patents in various industries, showcasing his versatility and creativity in inventing new solutions to complex problems.

Career Highlights: With a career spanning several decades, Thomas W. Bruice has established himself as a pioneer in the world of inventions. His innovative spirit and dedication to pushing the boundaries of what is possible have led to numerous breakthroughs.

Collaborations: Throughout his career, Thomas W. Bruice has collaborated with leading experts in the field, fostering a culture of innovation and knowledge-sharing that has resulted in remarkable inventions.

Conclusion: Thomas W. Bruice's passion for innovation and his relentless pursuit of excellence have solidified his reputation as a visionary inventor, inspiring generations to come.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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