The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 2007
Filed:
Feb. 28, 2003
Phillip D. Cook, Fallbrook, CA (US);
Guangyi Wang, Carlsbad, CA (US);
Thomas W. Bruice, Carlsbad, CA (US);
Nicholas A. Boyle, Encinitas, CA (US);
Janet M. Leeds, Encinitas, CA (US);
Jennifer L. Brooks, Encinitas, CA (US);
Marija Prhavc, Encinitas, CA (US);
Maria Eugenia Ariza, San Marcos, CA (US);
Patrick C. Fagan, Escondido, CA (US);
Yi Jin, Carlsbad, CA (US);
Vivek K. Rajwanshi, Vista, CA (US);
Kathleen D. Tucker, Escondido, CA (US);
Phillip D. Cook, Fallbrook, CA (US);
Guangyi Wang, Carlsbad, CA (US);
Thomas W. Bruice, Carlsbad, CA (US);
Nicholas A. Boyle, Encinitas, CA (US);
Janet M. Leeds, Encinitas, CA (US);
Jennifer L. Brooks, Encinitas, CA (US);
Marija Prhavc, Encinitas, CA (US);
Maria Eugenia Ariza, San Marcos, CA (US);
Patrick C. Fagan, Escondido, CA (US);
Yi Jin, Carlsbad, CA (US);
Vivek K. Rajwanshi, Vista, CA (US);
Kathleen D. Tucker, Escondido, CA (US);
Biota, Inc., Carlsbad, CA (US);
Abstract
The present invention relates to nucleoside diphosphate mimics and nucleoside triphosphate mimics, which contain diphosphate or triphosphate moiety mimics and optionally sugar-modifications and/or base-modifications. The nucleotide mimics of the present invention, in a form of a pharmaceutically acceptable salt, a pharmaceutically acceptable prodrug, or a pharmaceutical formulation, are useful as antiviral, antimicrobial, and anticancer agents. The present invention provides a method for the treatment of viral infections, microbial infections, and proliferative disorders. The present invention also relates to pharmaceutical compositions comprising the compounds of the present invention optionally in combination with other pharmaceutically active agents.