Singapore, Singapore

Thomas Hugo Keller

USPTO Granted Patents = 7 

 

 

Average Co-Inventor Count = 6.0

ph-index = 4

Forward Citations = 35(Granted Patents)


Location History:

  • Horsham, GB (2005)
  • Singapore, SG (2007 - 2023)

Company Filing History:


Years Active: 2005-2023

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7 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Thomas Hugo Keller

Introduction

Thomas Hugo Keller is an accomplished inventor based in Singapore, SG, known for his exceptional contributions to the field of therapeutic compounds and cancer treatment. With a total of 7 patents to his name, Keller has developed innovative solutions that address complex medical challenges, particularly in the realm of isoprenylcysteine carboxyl methyltransferase (ICMT) related disorders.

Latest Patents

Keller's latest patents reflect his commitment to advancing medical science. One of his prominent inventions involves compounds useful as inhibitors of isoprenylcysteine carboxyl methyltransferase. This invention focuses on compounds of general Formula (I), including their tautomers, enantiomers, solvates, hydrates, and pharmaceutically acceptable salts. The compounds are intended for therapeutic use, providing methods for treating disorders linked to ICMT, such as cancer and progeria. Additionally, Keller has created new heterobifunctional agents that facilitate the formation of protein-protein dimers and promote ubiquitination of proteins, with applications in treating diseases characterized by protein over-expression or malfunction.

Career Highlights

Throughout his career, Thomas Hugo Keller has been affiliated with prestigious organizations that have helped shape his innovative path. He has notably worked with Novartis AG, a global healthcare company, and the Agency for Science, Technology and Research (A*STAR), which focuses on driving scientific advancement in Singapore. His contributions in these roles have been instrumental in both research and practical applications of his inventions.

Collaborations

Keller has collaborated with notable professionals such as Bernard Cuenoud and Clive McCarthy, enhancing his innovative capabilities and expanding the reach of his work. These collaborations emphasize the importance of teamwork in the pursuit of breakthroughs in scientific research and development.

Conclusion

Thomas Hugo Keller stands out as a significant figure in the realm of inventions and innovations. His impressive portfolio of patents showcases his dedication to developing novel therapeutic solutions that address critical medical issues. Through his work, Keller continues to make a lasting impact on the fields of biochemistry and pharmacology, demonstrating the vital role that inventors play in advancing healthcare for future generations.

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