Montara, CA, United States of America

Thomas F Zioncheck


Average Co-Inventor Count = 3.3

ph-index = 5

Forward Citations = 82(Granted Patents)


Company Filing History:


Years Active: 1995-2007

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7 patents (USPTO):Explore Patents

Title: Thomas F. Zioncheck: Innovator in Pharmaceutical Compositions

Introduction

Thomas F. Zioncheck is a notable inventor based in Montara, CA (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of vascular endothelial cell growth factor (VEGF) variants. With a total of 7 patents to his name, Zioncheck's work has the potential to impact various therapeutic applications.

Latest Patents

Zioncheck's latest patents include innovative pharmaceutical compositions that feature variants of vascular endothelial cell growth factor. These variants have modifications in the C-terminal heparin binding domain, which result in reduced clearance rates for systemic administration at lower doses compared to native VEGF. This advancement allows for longer availability of the therapeutic effect. Another significant patent focuses on the modulation of eNOS activity and its therapeutic uses. This invention highlights the potential of VEGF or VEGF receptor agonists in up-regulating eNOS expression and activity, which can be beneficial in treating conditions such as hypertension, diabetes, and heart failure.

Career Highlights

Zioncheck is currently associated with Genentech, Inc., a leading biotechnology company known for its innovative approaches to drug development. His work at Genentech has allowed him to collaborate with other talented professionals in the field.

Collaborations

Some of his notable coworkers include Nishit B. Modi and Steven M. Chamow. Their collective expertise contributes to the advancement of research and development in the pharmaceutical industry.

Conclusion

Thomas F. Zioncheck's contributions to pharmaceutical innovations, particularly in the area of VEGF variants, demonstrate his commitment to improving therapeutic outcomes. His work continues to pave the way for advancements in medical treatments.

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