The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2002

Filed:

Feb. 14, 1997
Applicant:
Inventors:

Thomas F. Zioncheck, Montara, CA (US);

Geralyn G. DeGuzman, Daly City, CA (US);

Rodney Gene Keck, Castro Valley, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/518 ;
U.S. Cl.
CPC ...
C12N 1/518 ;
Abstract

Described herein are vascular endothelial cell growth factor (VEGF) variants having modifications in the C-terminus heparin binding domain. The variants exhibit reduced clearance rates for systemic administration generally at lower doses compared with native VEGF thus providing variants having longer availability for therapeutic effect.


Find Patent Forward Citations

Zioncheck, Thomas. (2002). Variants of vascular endothelial cell growth factor having altered pharmacological properties, and recombinant methods of production (U.S. Patent No. 6485942). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6485942

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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