Subhasish Tapadar

Title: Subhasish Tapadar: Innovator in Cancer Research

Introduction

Subhasish Tapadar is a notable inventor based in Atlanta, GA (US). He has made significant contributions to the field of cancer research through his innovative patents. With a total of 4 patents, Tapadar's work focuses on developing novel compounds and methods that have the potential to impact cancer treatment.

Latest Patents

Tapadar's latest patents include groundbreaking research on 3-(hydroxy)-pyridin-4(1H)-one compounds and methods of making and using the same. This patent provides compositions and methods for inhibiting histone lysine demethylases. Additionally, he has developed several new DFP-based KDM inhibitors that alter the velocity of HP1-mediated heterochromatin gene repression. Another significant patent involves small molecule inhibitors of G(alpha)i2 protein, which relates to novel compounds and methods to maintain the Gα2 protein in its inactive GDP-bound state. This research describes the knockdown or inhibition of Gα2, which negatively regulates the migration of breast and ovarian cancer cell lines. The novel compounds inhibit the migratory behavior of prostate cancer cell lines, specifically blocking the activation of Gα2 in oxytocin-stimulated prostate cancer PC3 cells.

Career Highlights

Throughout his career, Tapadar has worked with esteemed organizations such as Georgia Tech Research Corporation and Clark Atlanta University. His work in these institutions has allowed him to further his research and contribute to advancements in cancer treatment.

Collaborations

Tapadar has collaborated with notable colleagues, including Adegboyega K Oyelere and Verjine Khodaverdian. These partnerships have enhanced his research efforts and expanded the impact of his innovations.

Conclusion

Subhasish Tapadar is a prominent inventor whose work in cancer research is paving the way for new treatment options. His innovative patents and collaborations highlight his commitment to advancing medical science.