The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2023

Filed:

Mar. 20, 2019
Applicant:

Georgia Tech Research Corporation, Atlanta, GA (US);

Inventors:

Adegboyega K. Oyelere, Marietta, GA (US);

Verjine Khodaverdian, Atlanta, GA (US);

Subhasish Tapadar, Atlanta, GA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); C07D 401/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 401/06 (2013.01);
Abstract

Compositions and methods for inhibiting histone lysine demethylases are provided. Several new DFP-based KDM inhibitors which alter the velocity of HP1-mediated heterochromatin gene repression are provided.


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