Company Filing History:
7 out of 94 
1 out of 66 Years Active: 1988-1998
Title: The Innovative Contributions of Steve C. Chang
Introduction
Steve C. Chang is a notable inventor based in Franklin, MA (US), recognized for his significant contributions to the field of diagnostics and biochemistry. With a total of 8 patents to his name, Chang has developed innovative methods that enhance the efficiency and sensitivity of various assays.
Latest Patents
One of his latest patents is titled "Conjugation of ligand to immobilized protein in organic solvent." This invention presents a new method for immobilizing small molecules on solid supports via a macromolecular spacer. In this process, a protein or another macromolecule is first immobilized in an aqueous medium, followed by washing the solid support with an organic solvent. The small molecule is then coupled in an organic medium, which is followed by additional washes. These new solid phases are particularly useful for affinity purifications, immunoassays, and other binding assays, as well as for selecting binders through panning procedures.
Another significant patent is focused on "Nucleophilic polysubstituted aryl acridinium ester conjugates uses." This invention is directed towards novel assay methods that utilize nucleophilic polysubstituted aryl acridinium ester conjugates as tracers. The conjugates are prepared by covalent coupling of these novel esters with biological compounds, including small organic molecules such as Vitamin B12, folate, cortisol, estradiol, and thromboxane B2. These conjugates have proven useful in developing highly sensitive assays for analytes of diagnostic interest.
Career Highlights
Throughout his career, Steve C. Chang has worked with prominent companies in the diagnostics field, including Ciba Corning Diagnostics Corporation and Chiron Diagnostics Corporation. His work has significantly impacted the development of diagnostic tools and methodologies.
Collaborations
Chang has collaborated with notable professionals in his field, including Say-Jong Law and Stephen A. Palmacci. These collaborations have contributed to the advancement of his innovative projects and patents.
Conclusion
Steve C. Chang's contributions to the field of diagnostics through his innovative patents and collaborations highlight his role as a leading inventor. His work continues to influence the development of sensitive and efficient diagnostic methods.
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