The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 1998
Filed:
Nov. 06, 1995
Applicant:
Inventors:
Uri Piran, Sharon, MA (US);
Steve C Chang, Franklin, MA (US);
William J Riordan, Mansfield, MA (US);
James W Peterson, Attleboro, MA (US);
Edward M Sunshine, Plainville, MA (US);
Assignee:
Chiron Diagnostics Corporation, East Walpole, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; G01N / ;
U.S. Cl.
CPC ...
436527 ; 436526 ; 436529 ; 436530 ; 436533 ; 530807 ; 530811 ; 530814 ; 530815 ;
Abstract
A new method for immobilization of small molecules on solid supports via a macromolecular spacer has been developed. A protein or another macromolecule is first immobilized in an aqueous medium, and the solid support is than washed with an organic solvent. The small molecule is coupled in an organic medium, followed by organic medium washes. The new solid phases are useful for affinity purifications, immunoassays and other binding assays, and for selection of binders by panning procedures.