The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 1996
Filed:
Aug. 18, 1994
Applicant:
Inventors:
Say-Jong Law, Westwood, MA (US);
Steve C Chang, Franklin, MA (US);
Carol K Klukas, Pittsburgh, PA (US);
Christine A Vitkauskas, North Attleboro, MA (US);
Assignee:
Ciba Corning Diagnostics Corp., Medfield, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
436501 ; 435-71 ; 435-74 ; 435-6 ; 436500 ; 436505 ; 436518 ; 436544 ; 436546 ; 436800 ; 436817 ; 546107 ;
Abstract
This invention is directed to the novel assay methods utilizing nucleophilic polysubstituted aryl acridinium ester conjugates as the tracers. Conjugates prepared by covalent coupling of novel nucleophilic polysubstituted aryl acridinium esters with biological compounds including small organic molecules such as Vitamin B12, folate, cortisol, estradiol, and thromboxane B2, were found useful in the development of highly sensitive assays for the analytes of diagnostic interest.