Company Filing History:
18 out of 460 
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2 out of 3 Years Active: 2011-2025
Title: **The Innovative Mind of Stephan Jenne: A Pioneer in Engineered Enzymes**
Introduction
Stephan Jenne is a distinguished inventor based in Foster City, California, who has made significant contributions to the field of biotechnology. With a remarkable portfolio of 18 patents, Jenne stands out for his innovative approaches to enzymatic functions, particularly in the development of engineered polypeptides.
Latest Patents
One of Jenne's latest inventions is centered on engineered leucine decarboxylases. This invention provides engineered leucine decarboxylase (LDC) polypeptides, which are enhanced for catalytic activity and exhibit reduced sensitivity to proteolysis. Moreover, these engineered polypeptides demonstrate increased tolerance to low pH environments and improved storage stability. The invention also outlines methods for utilizing these compositions in therapeutic and industrial applications.
Another notable patent involves engineered imine reductases. This application presents engineered polypeptides with imine or oxime reductase activity, along with methods for the reductive amination of ketone and amine compounds. These engineered polypeptides can be utilized to convert a variety of ketone and amine substrates into secondary and tertiary amine products, showcasing Jenne's dedication to advancing biocatalysis.
Career Highlights
Jenne's professional journey has seen him collaborate with leading companies in the biotechnology sector, including Codexis, Inc. and Pfizer Corporation. His innovative work has not only contributed to his personal success but has also aided these organizations in their mission to provide groundbreaking solutions in medicine and industry.
Collaborations
Throughout his career, Jenne has had the pleasure of working alongside talented individuals such as Rama Voladri and Emily Mundorff. These collaborations have undoubtedly enriched his inventiveness and led to the creation of impactful technologies.
Conclusion
Stephan Jenne exemplifies the spirit of innovation in biotechnological inventions. With his extensive experience and dedication to engineering novel enzymes, he continues to pave the way for advancements that benefit both therapeutic and industrial sectors. As his work progresses, it will be exciting to see the new horizons he will explore, shaping the future of biotechnology.