The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2024

Filed:

May. 26, 2021
Applicant:

Codexis, Inc., Redwood City, CA (US);

Inventors:

Margie Tabuga Borra-Garske, Palo Alto, CA (US);

Oscar Alvizo, Fremont, CA (US);

Melissa Ann Mayo, Foster City, CA (US);

Stephan Jenne, Foster City, CA (US);

Auric Anthony Sowell-Kantz, Fairfax, CA (US);

Carmela Molinaro, Colonia, NJ (US);

Assignee:

Codexis, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/06 (2006.01); C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0028 (2013.01); C12N 9/0036 (2013.01); C12Y 105/01 (2013.01); C12Y 106/00 (2013.01);
Abstract

The present application provides engineered polypeptides having imine or oxime reductase activity, polynucleotides encoding the engineered polypeptides, host cells capable of expressing the engineered polypeptides, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.


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