Stefaan De Smedt

USPTO Granted Patents = 11 (Patent Applications = 12)

EPO Patents = 6 (Patent Applications = 19)

Average Co-Inventor Count = 4.1

ph-index = 2

Forward Citations = 24(Granted Patents)

Company Filing History:

Centre National De La Recherche Scientifique

patents

4. 1 out of 10

Université Des Sciences Et Technologies De Lille 1

patents

5. 1 out of 33

Universidad Complutense De Madrid

patents

6. 1 out of 84

Universiteit Antwerpen

patents

7. 1 out of 3

Universitair Ziekenhuis Antwerpen

where one patent can have more than one assignee

Years Active: 2008-2025

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11 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12421486 - Method to increase the permeability of the plasma membrane of cells and a structure suitable for use in such method (2025-09-23),

2. 12419844 - Composition for treatment of vitreous disease or disorder (2025-09-23),

3. 12091655 - Method to selectively permeabilize and/or fragmentize cells (2024-09-17),

4. 11712484 - Carbon-based particles for vapour bubble generation (2023-08-01),

5. 11213573 - Particles comprising surfactant protein B and one or more lipids (2022-01-04),

6. 11033572 - Molecular adjuvants for enhanced cytosolic delivery of active agents (2021-06-15),

7. 10746730 - Method and system for characterizing extracellular vesicles (2020-08-18),

8. 9483440 - Method and system for dispersion measurements (2016-11-01),

9. 8928875 - Methods and systems for optical characterisation (2015-01-06),

10. 8735172 - Method and device for the manipulation of microcarriers for an identification purpose (2014-05-27),

11. 7432308 - Therapeutic compositions for the treatment of a respiratory tract disease (2008-10-07),

Title: Stefaan De Smedt: Innovator in Cell Permeability and Vitreous Treatment

Introduction

Stefaan De Smedt is a notable inventor based in Mariakerke, Belgium. He has made significant contributions to the field of biomedical engineering, particularly in methods that enhance cell permeability and treat vitreous diseases. With a total of 11 patents to his name, his work has the potential to impact various medical applications.

Latest Patents

Among his latest patents is a method to increase the permeability of the plasma membrane of cells. This invention involves introducing at least one cell on or near a structure comprising particles that can absorb electromagnetic radiation. The particles are embedded in the material of the structure at a concentration ranging from 0.001 vol % to 20 vol %. Notably, at least 60% of these particles are embedded in such a way that the shortest distance between them and the free area surface of the structure ranges from 1 nm to 500 nm. This method is designed for use in photothermal processes to permeabilize cells. Another significant patent is a composition for the treatment of vitreous diseases or disorders. This composition includes particles that serve as a light-sensitizing agent, designed for mobility in the vitreous and for binding to collagen aggregates, such as floaters.

Career Highlights

Stefaan De Smedt has had a distinguished career, working with esteemed

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