The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Jan. 18, 2018
Applicant:
Universiteit Gent, Ghent, BE;
Inventors:
Koen Raemdonck, Ghent, BE;
Stefaan De Smedt, Mariakerke, BE;
Assignee:
Universiteit Gent, Ghent, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 31/713 (2006.01); A61K 9/06 (2006.01); A61K 9/51 (2006.01); A61K 31/137 (2006.01); A61K 31/404 (2006.01); A61K 31/4545 (2006.01); A61K 31/4704 (2006.01); A61K 39/39 (2006.01); A61K 47/36 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 9/06 (2013.01); A61K 9/513 (2013.01); A61K 31/137 (2013.01); A61K 31/404 (2013.01); A61K 31/4545 (2013.01); A61K 31/4704 (2013.01); A61K 39/39 (2013.01); A61K 47/36 (2013.01); A61K 45/06 (2013.01);
Abstract
The present invention relates to a method and compositions for optimized intracellular delivery of active agents, in particular nucleic acids, using a specific class of adjuvants. The method and compositions of the invention enhance cytosolic release of the agents and can be used for the treatment of various disorders.