The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2025

Filed:

Sep. 21, 2020
Applicant:

Trince Bv, Ghent, BE;

Inventors:

Kevin Braeckmans, Lokeren, BE;

Ranhua Xiong, Ghent, BE;

Stefaan De Smedt, Mariakerke, BE;

Assignee:

Trince BV, Ghent, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/42 (2006.01); C12N 13/00 (2006.01);
U.S. Cl.
CPC ...
C12M 35/02 (2013.01); C12N 13/00 (2013.01);
Abstract

The invention relates to a method to increase the permeability of the plasma membrane of cells by introducing at least one cell on or near a structure comprising particles able to absorb electromagnetic radiation. The particles, present in a concentration ranging between 0.001 vol % and 20 vol %, are embedded in the material of the structure. At least 60% of the particles present in the structure are embedded in the material in such a way that the shortest distance L between these particles and the free area surface S of the structure ranges between 1 nm and 500 nm. The invention further relates to a structure suitable for use in a photothermal process to permeabilize cells and to the use of such structure.


Find Patent Forward Citations

Loading…