Location History:
- Beverly, MA (US) (2005)
- Wenham, MA (US) (2013 - 2018)
- Ipswich, MA (US) (2021 - 2023)
Company Filing History:
Years Active: 2005-2023
Title: Innovations of Sriharsa Pradhan in Chromatin Analysis
Introduction
Sriharsa Pradhan is a notable inventor based in Wenham, MA (US). He has made significant contributions to the field of molecular biology, particularly in the analysis of chromatin. With a total of 10 patents to his name, Pradhan's work has advanced our understanding of genetic material and its implications in diagnostics.
Latest Patents
One of Pradhan's latest patents is focused on the "Analysis of chromatin using a nicking enzyme." This invention provides various compositions and methods for analyzing chromatin. The composition may include a mixture of a nicking enzyme, four dNTPs, at least one labeled dNTP, and optionally, a polymerase. The method involves obtaining a sample containing chromatin, reacting it with the composition to selectively label open chromatin, and analyzing the labeled sample.
Another significant patent is titled "Compositions and methods for detecting molecular targets on chromosomal DNA." This invention offers compositions, methods, and kits for identifying the presence and location of a target in chromosomal DNA. It features a nicking endonuclease fused to a binding domain that can bind to a constant region of an antibody. This allows for direct binding to a target or via an antibody that binds to the target. The presence and location of the target may correspond to a phenotype or pathology in a biopsy or other cell sample, which is crucial for diagnostic purposes.
Career Highlights
Sriharsa Pradhan is currently associated with New England Biolabs, Inc., where he continues to innovate in the field of molecular biology. His work has been instrumental in developing methods that enhance the analysis of chromatin and DNA.
Collaborations
Pradhan has collaborated with notable colleagues, including Hang-Gyeong Chin and George R Feehery. These collaborations have further enriched his research and contributed to the advancements in his field.
Conclusion
Sriharsa Pradhan's contributions to chromatin analysis through his innovative patents have significantly impacted molecular biology. His work continues to pave the way for advancements in diagnostics and genetic research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.