Location History:
- Cary, NC (US) (2020 - 2021)
- Durham, NC (US) (1998 - 2022)
Company Filing History:
15 out of 2,009 
1 out of 40 
1 out of 3,539 
Years Active: 1998-2022
Title: The Innovative Contributions of Smita K Nair
Introduction: Smita K Nair, based in Durham, NC, is a prominent inventor known for her groundbreaking work in the field of immunotherapy. With a remarkable portfolio of 15 patents, she has made significant strides in predicting tumor responses and enhancing the efficacy of cancer treatments.
Latest Patents: Among her latest innovations are methods for predicting tumor response to immunotherapy. This patent outlines techniques for testing tumor samples, determining mutational burden, and assessing expression profiles to predict responsiveness to the immunotherapy agent PVSRIPO. Those patients predicted to respond are treated with PVSRIPO, while others may receive alternative treatments based on their predictive analysis. Another important patent focuses on the compositions and methods for activating antigen presenting cells using chimeric poliovirus. This innovation allows for the activation of these cells in vitro, ex vivo, or in vivo, with the potential to be therapeutically administered either alone or alongside an antigen or vaccine. This therapeutic administration of activated antigen presenting cells can serve as an adjuvant to enhance the effectiveness of other therapies.
Career Highlights: Smita has an impressive career marked by her work with Duke University and Argos Therapeutics, Inc., where she has been instrumental in research and development in her area of expertise.
Collaborations: Throughout her career, Smita K Nair has collaborated with esteemed colleagues, including Eli Gilboa and David J Boczkowski. These collaborations have contributed to the advancement of cancer therapies and the understanding of immunotherapy.
Conclusion: Smita K Nair's contributions to the field of cancer research and immunotherapy exemplify the power of innovation in transforming medical treatments. With her 15 patents, she continues to pave the way for new approaches to cancer treatment, ultimately improving the lives of patients worldwide.