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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10744170 B1

PDFFull Text
Date of Patent:
Aug. 18, 2020

Filed:

Oct. 14, 2016

Combination treatment

Applicant:

Duke University, Durham, NC (US);

Inventors:

Darell D. Bigner, Mebane, NC (US);

Matthias Gromeier, Durham, NC (US);

Smita Nair, Cary, NC (US);

Vidyalakshmi Chandramohan, Durham, NC (US);

Assignee:

Duke University, Durham, NC (US);

Attorney:

Banner & Witcoff, Ltd.

Primary Examiner:

Robert M Kelly

Int. Cl.
CPC ...
A61K 35/768 (2015.01); A61K 39/13 (2006.01); A61K 39/395 (2006.01); A61K 9/127 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C12N 15/85 (2006.01); A61K 39/39 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/768 (2013.01); A61K 9/127 (2013.01); A61K 39/13 (2013.01); A61K 39/39 (2013.01); A61K 39/39541 (2013.01); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); C12N 7/00 (2013.01); C12N 15/85 (2013.01); A61K 2039/505 (2013.01); A61K 2300/00 (2013.01); C07K 2317/76 (2013.01); C12N 2770/32621 (2013.01); C12N 2770/32632 (2013.01); C12N 2840/203 (2013.01); Y02A 50/466 (2018.01);
Abstract

Human clinical use of a chimeric poliovirus construct has demonstrated excellent anti-tumor effect. Combination with immune checkpoint inhibitors increases the anti-tumor effect. Tumors of different types are susceptible to the combination treatment, including but not limited to melanoma, glioglastoma, renal cell carcinoma, prostate cancer, breast cancer, lung cancer, medulloblastoma, and colorectal cancer.

Find Patent Forward Citations

Bigner, Darell. (2020). Combination treatment (U.S. Patent No. 10744170). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10744170

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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