San Mateo, CA, United States of America

Siyuan Chen

USPTO Granted Patents = 37 

 

Average Co-Inventor Count = 3.7

ph-index = 18

Forward Citations = 901(Granted Patents)


Location History:

  • San Jose, CA (US) (2017)
  • San Francisco, CA (US) (2020)
  • San Mateo, CA (US) (2016 - 2023)
  • Santa Clara, CA (US) (2017 - 2023)

Company Filing History:


Years Active: 2016-2025

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37 patents (USPTO):Explore Patents

Title: Siyuan Chen - Innovator in Oligonucleic Acid Technologies

Introduction

Siyuan Chen, based in San Mateo, California, is an accomplished inventor with an impressive portfolio of 34 patents. His groundbreaking work focuses on the development of oligonucleic acid technologies that hold significant promise for advancements in biological research and therapeutics.

Latest Patents

Two of Chen's latest patents showcase his innovative approaches in the field. The first patent, titled "Oligonucleic acid variant libraries and synthesis thereof," reveals methods for generating highly accurate oligonucleic acid libraries encoding predetermined variants. These libraries can be fully saturated with variants or selectively designed, enabling the generation of variant RNA, DNA, and protein populations. This method is particularly beneficial for identifying species with varying activities, providing applications in biological regulation and therapeutic design.

The second patent, "Polynucleotides, reagents, and methods for nucleic acid hybridization," presents compositions and methods facilitating accurate hybridization of polynucleotide libraries to target sequences. These innovations enhance Next Generation Sequencing applications by reducing off-target binding and optimizing workflow efficiency, thereby sustaining the evolution of genomic research.

Career Highlights

Siyuan Chen has contributed significantly to the field through his tenure at notable companies such as Twist Bioscience Corporation and Agilent Technologies, Inc. His work has positioned him as a key player in advancing nucleic acid technologies that are critical for scientific and medical communities.

Collaborations

During his career, Chen has collaborated with distinguished colleagues, including William Banyai and Bill James Peck. These partnerships have fostered a collaborative environment, leading to innovative solutions and developments within the research community.

Conclusion

Siyuan Chen exemplifies the role of a modern inventor through his contributions to oligonucleic acid technologies. His patents not only enhance scientific understanding but also pave the way for therapeutic advances in medicine. As he continues to innovate, the implications of his work are poised to make a lasting impact on the fields of biology and healthcare.

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