The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2022
Filed:
May. 20, 2019
Twist Bioscience Corporation, San Francisco, CA (US);
Ramsey Ibrahim Zeitoun, San Francisco, CA (US);
Siyuan Chen, San Mateo, CA (US);
Richard Gantt, San Francisco, CA (US);
Kristin D. Butcher, San Francisco, CA (US);
E. Hutson Chilton, San Francisco, CA (US);
Twist Bioscience Corporation, South San Francisco, CA (US);
Abstract
Provided herein are compositions, methods and systems relating to libraries of polynucleotides such that the libraries allow for accurate and efficient hybridization after binding to target sequences. Further provided herein are probes, blockers, additives, buffers, and methods that result in improved hybridization. Such compositions and methods are useful for improvement of Next Generation Sequencing applications, such as reducing off-target binding or reducing workflow times.