North Wales, PA, United States of America

Shawn DeFrees

USPTO Granted Patents = 61 

 

Average Co-Inventor Count = 2.6

ph-index = 26

Forward Citations = 1,564(Granted Patents)

Forward Citations (Not Self Cited) = 637(Oct 12, 2025)


Inventors with similar research interests:


Company Filing History:


Years Active: 2005-2020

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Areas of Expertise:
Glycopegylation
Glycosylation
Fibroblast Growth Factor
Therapeutic Proteins
Nucleotide Sugars
Conjugated Molecules
Peptide Conjugates
Glycoproteins
Hydrophobic Interaction Chromatography
Granulocyte Colony Stimulating Factor
Erythropoietin
Synthetic Gangliosides
61 patents (USPTO):Explore Patents

Title: Innovations and Achievements of Shawn DeFrees

Introduction

Shawn DeFrees, a prominent inventor located in North Wales, PA, has made significant contributions to the field of biotechnology, with an impressive portfolio of 61 patents. His work focuses on innovative methods for treating various disorders, highlighting his dedication to advancing medical science and improving patient outcomes.

Latest Patents

Among Shawn's latest patents is a groundbreaking invention titled "Method of treating fibroblast growth factor 21 (FGF-21) deficiency." This invention pertains to mutants of Fibroblast Growth Factor (FGF), specifically FGF-20 and FGF-21, which are engineered to contain newly introduced N-linked or O-linked glycosylation sites. The patent includes polynucleotide coding sequences for the mutants, expression cassettes, and methods for producing the mutants, along with pharmaceutical compositions and applications for their use.

Another notable invention is related to "Glycolipids as treatment for disease." This patent encompasses compounds, compositions, and methods aimed at treating various disorders, including cancer, hyperinsulinemia, and atypical Parkinson's disease, among others. Each invention underscores DeFrees' commitment to addressing complex health challenges.

Career Highlights

Shawn DeFrees has collaborated with leading companies in the biotechnology sector, including Novo Nordisk A/S and Neose Technologies, Inc. His work at these institutions has allowed him to explore innovative solutions in genetics and disease treatment, ensuring that his inventions have practical applications in the medical field.

Collaborations

Throughout his career, DeFrees has worked alongside notable professionals such as David A. Zopf and Caryn Bowe. These collaborations have enriched his research and development efforts, contributing to the successful filing and granting of numerous patents that push the boundaries of current medical practices.

Conclusion

Shawn DeFrees continues to be a trailblazer in the field of biotechnology, with his extensive patent portfolio reflecting his inventive spirit and commitment to advancing healthcare solutions. His work not only showcases the impact of innovation in medicine but also inspires future inventors and researchers in their pursuit of technological advancements.

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