The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2020
Filed:
Nov. 30, 2015
Applicant:
89bio Ltd., Herzliya, IL;
Inventor:
Shawn DeFrees, North Wales, PA (US);
Assignee:
89BIO LTD., Herzliya, IL;
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); C07K 14/50 (2006.01); C12P 21/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1825 (2013.01); A61K 47/549 (2017.08); A61K 47/60 (2017.08); C07K 14/50 (2013.01); C12P 21/005 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to mutants of Fibroblast Growth Factor (FGF), particularly FGF-20 and FGF-21, which contain newly introduced N-linked or O-linked glycosylation site(s). The polynucleotide coding sequences for the mutants, expression cassettes comprising the coding sequences, cells expressing the mutants, and methods for producing the mutants are also disclosed. Further disclosed are pharmaceutical compositions comprising the mutants and method for using the mutants.