Company Filing History:
6 out of 8,369 
3 out of 2,961 
Years Active: 2018-2021
Title: Shahar Alon: Innovator in Genomic Analysis
Introduction
Shahar Alon is a prominent inventor based in Cambridge, MA, known for his significant contributions to the field of genomic analysis. With a total of six patents to his name, Alon has developed innovative methods that enhance the understanding of polynucleotides, particularly genomic DNA and RNA.
Latest Patents
One of Alon's latest patents is focused on in situ ATAC sequencing. This invention provides methods for analyzing polynucleotides such as genomic DNA. The method involves preparing and amplifying a genomic DNA library in situ within a fixed biological sample. It includes treating the sample with an insertional enzyme complex to produce tagged fragments of genomic DNA, followed by circularizing and amplifying these fragments.
Another notable patent is related to multiplexed signal amplified FISH via splinted ligation amplification and sequencing. This method amplifies at least one target RNA in a fixed biological sample. It involves incubating the sample with a pair of polynucleotides that are complementary to non-overlapping and proximal sequences of the target RNA. The polynucleotide pair hybridizes to the target RNA, is ligated using a ligase, and the ligation product is then amplified. This method allows for the detection, quantification, and sequencing of the amplification product in situ.
Career Highlights
Shahar Alon has worked with prestigious institutions such as the Massachusetts Institute of Technology and Harvard College. His work at these institutions has significantly advanced the field of genomic research and analysis.
Collaborations
Alon has collaborated with notable figures in the scientific community, including Edward Stuart Boyden and Fei Chen. These collaborations have further enriched his research and innovations in genomic analysis.
Conclusion
Shahar Alon is a distinguished inventor whose work in genomic analysis has led to groundbreaking patents that enhance our understanding of DNA and RNA. His contributions continue to influence the field and pave the way for future innovations.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.