Company Filing History:
5 out of 3,685 
5 out of 1,371 
5 out of 24 Years Active: 1993-2001
Title: Savvas C Makrides: Innovator in Complement Biology
Introduction
Savvas C Makrides is a notable inventor based in Bedford, MA (US), recognized for his contributions to the field of complement biology. He holds a total of seven patents, showcasing his innovative approach to addressing complex biological challenges.
Latest Patents
One of his latest patents focuses on the Human C3b/C4b receptor (CR1). This invention relates to the CR1 gene and its encoded protein, providing insights into CR1 nucleic acid sequences and fragments comprising 70 nucleotides, along with their encoded peptides or proteins consisting of 24 amino acids. The invention emphasizes the expression of the CR1 protein and its fragments, which have significant applications in diagnosing and treating disorders associated with complement activity, as well as various immune system and inflammatory disorders. Specific embodiments of this invention detail the cloning, nucleotide sequence, and deduced amino acid sequence of a full-length CR1 cDNA and its fragments. Additionally, the expression of a secreted CR1 molecule lacking a transmembrane region is described, which has been shown to reduce damage caused by inflammation, decrease myocardial infarct size, and prevent reperfusion injury.
Career Highlights
Throughout his career, Savvas C Makrides has made significant strides in the field of biomedical research. His work has been instrumental in advancing our understanding of the complement system and its implications for human health.
Collaborations
He has collaborated with esteemed colleagues such as Douglas T Fearon and Lloyd B Klickstein, further enhancing the impact of his research through shared expertise and knowledge.
Conclusion
Savvas C Makrides stands out as a prominent inventor whose work in complement biology has the potential to transform therapeutic approaches to immune and inflammatory disorders. His innovative patents reflect a commitment to advancing medical science and improving patient outcomes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.