The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 1999
Filed:
Jun. 06, 1995
Douglas T Fearon, Baltimore, MD (US);
Lloyd B Klickstein, Brookline, MA (US);
Winnie W Wong, Newton, MA (US);
Gerald R Carson, Wellesley, MA (US);
Michael F Concino, Newton, MA (US);
Stephen H Ip, Sudbury, MA (US);
Savvas C Makrides, Bedford, MA (US);
Henry C Marsh, Jr, Reading, MA (US);
The Johns Hopkins University, Baltimore, MD (US);
Brigham & Women's Hospital, Boston, MA (US);
T Cell Sciences, Inc., Needham, MA (US);
Abstract
Human complement receptor type 1 (CR1). Nucleic acid molecules encoding full-length CR1 protein and fragments thereof having complement regulatory activity are described, as well as recombinant CR1 protein and polypeptides, vectors for their expression, and cell lines expressing or bearing DNA molecules encoding such proteins and polypeptides, including a soluble CR1 polypeptide consisting of the extracellular 30 short consensus repeat domains of the mature CR1 protein. The nucleic acids and polypeptides described are useful in diagnosis and treatment of disorders involving complement activity and inflammation. Compositions useful in therapeutic applications are also disclosed.