Company Filing History:
Years Active: 1993-2002
Title: Innovations and Contributions of Douglas T Fearon
Introduction
Douglas T Fearon is a prominent inventor based in Baltimore, MD, known for his significant contributions to the field of immunology. He holds a total of seven patents, showcasing his innovative approach to solving complex medical challenges. His work primarily focuses on complement regulatory molecules and their applications in therapeutic settings.
Latest Patents
One of his latest patents is centered around soluble complement regulatory molecules. This invention involves a soluble recombinant fused protein that remains stable in the mammalian circulatory system. It comprises a polypeptide with a recognition site for a target molecule, such as a complement receptor site, which is joined to the N-terminal end of an immunoglobulin chain. This invention is particularly useful for inhibiting complement activation or complement-dependent cellular activation in mammals.
Another notable patent is related to the Human C3b/C4b receptor (CR1). This invention pertains to the CR1 gene and its encoded protein, including nucleic acid sequences and fragments that have significant implications for diagnosing and treating disorders involving complement activity and various immune system or inflammatory disorders. The invention also describes the expression of a secreted CR1 molecule that is beneficial in reducing inflammation damage and preventing myocardial infarct size.
Career Highlights
Douglas T Fearon has had a distinguished career, working with esteemed institutions such as The Johns Hopkins University and The Brigham and Women's Hospital, Inc. His research has led to groundbreaking advancements in understanding the immune system and developing therapeutic strategies.
Collaborations
Throughout his career, Fearon has collaborated with notable colleagues, including Lloyd B Klickstein and Winnie W Wong. These collaborations have further enriched his research and contributed to the advancement of immunological science.
Conclusion
Douglas T Fearon is a remarkable inventor whose work has significantly impacted the field of immunology. His innovative patents and collaborations highlight his dedication to advancing medical science and improving therapeutic outcomes.
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