The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 1993
Filed:
Sep. 24, 1990
Douglas T Fearon, Baltimore, MD (US);
Lloyd B Klickstein, Brookline, MA (US);
Winnie W Wong, Newton, MA (US);
Gerald R Carson, Wellesley, MA (US);
Michael F Concino, Newton, MA (US);
Stephen H Ip, Sudbury, MA (US);
Savvas Makrides, Bedford, MA (US);
Henry C Marsh, Jr, Reading, MA (US);
The Johns Hopkins University, Baltimore, MD (US);
Brigham and Women's Hospital, Boston, MA (US);
T Cell Sciences, Inc., Cambridge, MA (US);
Abstract
The present invention relates to compositions comprising soluble complement receptor 1 (CR1) and a thrombolytic agent. In a specific embodiment, the thrombolytic agent is anisoylated human plasminogen-streptokinase activator complex (ASPAC). The invention further relates to methods for treating thrombotic conditions in humans and animals by administering a composition comprising soluble CR1 and a thrombolytic agent. In particular, the compositions and methods are useful both for reducing reperfusion injury and ameliorating the other effects of myocardial infarction.