Otake, Japan

Ryozo Numazawa


Average Co-Inventor Count = 3.5

ph-index = 6

Forward Citations = 181(Granted Patents)


Location History:

  • Tokyo, JP (1989)
  • Otake, JP (1980 - 1995)
  • Ohtake, JP (1986 - 1995)
  • Nagoya, JP (1994 - 1996)

Company Filing History:


Years Active: 1980-1996

where 'Filed Patents' based on already Granted Patents

12 patents (USPTO):

Title: The Innovations of Ryozo Numazawa

Introduction

Ryozo Numazawa, an accomplished inventor based in Otake, Japan, has made significant contributions to the field of biotechnology. With a remarkable portfolio of 12 patents, his work focuses on the development of innovative processes and products, particularly in the realm of esterase enzymes.

Latest Patents

Numazawa's recent patents highlight his expertise in molecular biology and enzyme technology. One of his notable inventions is related to esterase genes, recombinant plasmids, and transformants. This invention pertains to a DNA fragment that encodes an amino acid sequence of esterase, capable of asymmetrically hydrolyzing carboxylic acid esters. This technology facilitates the production of optically active carboxylic acids and their enantiomeric esters, which have important applications in pharmaceuticals.

Another significant patent focuses on the process for producing N-(3-acetylthio-2-D-methylpropionyl)-L-proline, a precursor for captopril, a well-known antihypertensive agent. This process involves novel reactions with thioacetic acid and methyl methacrylate, followed by biological and asymmetric hydrolysis using microorganisms like Pseudomonas to yield valuable pharmaceutical compounds.

Career Highlights

Ryozo Numazawa currently works at Mitsubishi Rayon Company, Limited, where he utilizes his skills in biochemistry and molecular biology to propel innovations forward. His career is marked by a series of groundbreaking inventions, showcasing his dedication to advancing science and technology in his field.

Collaborations

In his research endeavors, Numazawa has collaborated with fellow scientists, including Akihiro Sakimae and Hisao Onishi. These collaborations emphasize the importance of teamwork in the pursuit of innovative solutions and the sharing of knowledge within the scientific community.

Conclusion

Ryozo Numazawa exemplifies the spirit of innovation through his extensive patent portfolio and collaborative efforts. His work continues to pave the way for advancements in biotechnology, further establishing his reputation as a leading inventor in the industry. As he pushes the boundaries of what is possible, his contributions hold promise for significant advancements in pharmaceuticals and other related fields.

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