Bethesda, MD, United States of America

Robert R Clarke


Average Co-Inventor Count = 5.2

ph-index = 2

Forward Citations = 13(Granted Patents)


Location History:

  • Bethesda, MD (US) (1992)
  • Washington, DC (US) (2017)
  • Rockville, MD (US) (2000 - 2020)

Company Filing History:


Years Active: 1992-2020

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5 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Robert R. Clarke

Introduction: Robert R. Clarke, a distinguished inventor based in Bethesda, MD, is known for his significant contributions to the fields of cancer research, diabetes, and obesity through his innovative inventions. With a total of five patents to his name, Clarke has made strides in developing small molecule inhibitors and methods to combat critical health challenges.

Latest Patents: Clarke's latest patents focus on the development of small molecule inhibitors of XBP1 splicing by IRE1α, providing methods for their application in treating or preventing cancers such as endocrine-resistant breast cancer, as well as diabetes and obesity. Another notable invention pertains to methods of inhibiting the proliferation of estrogen-independent cancer cells. This patent outlines techniques for reducing the expression or activity of specific genes, including BLOC1S1, CDC2L1, and several others that play a role in cell growth and cancer progression.

Career Highlights: Currently, Robert R. Clarke is affiliated with Georgetown University, where his research and innovative approaches continue to make an impact in the scientific community. His work is crucial in enhancing the understanding of disease pathology and the development of novel therapeutic strategies.

Collaborations: Clarke has collaborated with esteemed colleagues, including Alem Ghiorghis and Charles F. Hammer. Together, they contribute to the advancement of health-related technologies and research, fostering a collaborative environment that enhances innovation.

Conclusion: Robert R. Clarke exemplifies the spirit of innovation in scientific research. Through his patented inventions and impactful collaborations, he is making significant strides in addressing critical health issues. His work continues to inspire new ideas and advancements in the fields of medicine and biotechnology.

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