The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2017

Filed:

Sep. 14, 2012
Applicants:

Louis M. Weiner, Washington, DC (US);

Rochelle E. Nasto, Washington, DC (US);

Robert Clarke, Washington, DC (US);

Erica Golemis, Philadelphia, PA (US);

Ilya Serebriiskii, Rockledge, PA (US);

Inventors:

Louis M. Weiner, Washington, DC (US);

Rochelle E. Nasto, Washington, DC (US);

Robert Clarke, Washington, DC (US);

Erica Golemis, Philadelphia, PA (US);

Ilya Serebriiskii, Rockledge, PA (US);

Assignee:

Georgetown University, Washington, DC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2320/11 (2013.01);
Abstract

The invention relates to methods of inhibiting the growth or proliferation of a cell, the method comprising reducing the expression or activity of at least one gene in the cell selected from the group consisting of BLOC1S1, CDC2L1, CNOT1, DDX54, EIF3I, FANCG, FBP1, IER2, KIF1A, LCK, NR2F1, PNRC1, POLR2A, POLR2B, POLR2C, PRPF6, PSMB4, PSMC5, PSMD1, RPS2, SCNN1A, SF3A3, TAF2, TOB1 and TSC22D4.


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