Durham, NC, United States of America

Robert Anthony Mook

USPTO Granted Patents = 19 


Average Co-Inventor Count = 6.1

ph-index = 9

Forward Citations = 297(Granted Patents)


Location History:

  • Durham, NC (US) (2006 - 2016)
  • Chapel Hill, NC (US) (1991 - 2021)

Company Filing History:


Years Active: 1991-2021

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19 patents (USPTO):

Title: The Innovations of Robert Anthony Mook: A Trailblazer in Therapeutics

Introduction

Robert Anthony Mook, an accomplished inventor based in Durham, NC, has made significant contributions to the field of biomedicine, holding an impressive 19 patents. His innovative work focuses on the modulation of biological signaling pathways and immune checkpoints, driving advancements in therapeutic applications for various diseases.

Latest Patents

Among his latest patents, Mook has developed chemical modulators of signaling pathways with therapeutic uses. These methods target diseases associated with the dysregulation of the Wnt/Frizzled signaling pathway. His innovations include identifying subjects in need of therapy, administering inhibitors that affect this pathway, and formulating pharmaceutical compositions, all aimed at treating conditions such as cancer, bacterial and viral infections, lupus, type II diabetes, nonalcoholic steatohepatitis (NASH), and nonalcoholic fatty liver disease (NAFLD).

Another notable patent involves chemical modulators of immune checkpoints, showcasing his contributions to oncology and infectious diseases. This patent details compounds and pharmaceutical compositions designed to down-regulate immune checkpoints like PD-1, PD-L1, and CTLA-4, thereby improving treatment efficacy for cancer and viral infections.

Career Highlights

Throughout his career, Mook has collaborated with prestigious organizations such as SmithKline Beecham Corporation and Duke University. His roles at these institutions have enabled him to focus on groundbreaking research and the development of therapeutic innovations.

Collaborations

Mook has worked closely with fellow researchers, including Mui Cheung and Wei Chen, contributing to the advancement of science and creation of viable therapeutic options. Their teamwork has played an essential role in driving the breakthroughs found in Mook's patents.

Conclusion

Robert Anthony Mook exemplifies a dedicated inventor whose work has the potential to significantly impact health outcomes. His numerous patents and collaborative efforts with leading institutions highlight his role in shaping the future of medical therapies, particularly in the fight against challenging diseases.

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