The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2021
Filed:
Jun. 24, 2016
Duke University, Durham, NC (US);
Wei Chen, Chapel Hill, NC (US);
Robert A. Mook, Jr., Chapel Hill, NC (US);
Jiangbo Wang, Durham, NC (US);
Xiu-rong Ren, Durham, NC (US);
Minyong Chen, Durham, NC (US);
Lawrence S. Barak, Durham, NC (US);
Herbert Kim Lyerly, Chapel Hill, NC (US);
David Needham, Durham, NC (US);
Duke University, Durham, NC (US);
Abstract
Described are methods of treating a disease associated with dysregulation of the Wnt/Frizzled signaling pathway. The methods include identifying subjects in need of therapy, administering inhibitors of the Wnt/Frizzled signaling pathway, pharmaceutical compositions including the inhibitors, and methods of using the compounds and compositions for treating cancer, bacterial and viral infection, lupus, type II diabetes, nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD) in a subject.