This inventor holds 3 USPTO granted patents and 1 published patent application. Top assignee: Syracuse University. Active years: 2013-2018.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Syracuse, NY (US) (2013 - 2016)
- Billerica, MA (US) (2018)
Company Filing History:
Years Active: 2013-2018
Title: The Innovative Contributions of Rebecca A. Bader
Introduction
Rebecca A. Bader is a prominent inventor based in Syracuse, NY (US). She has made significant contributions to the field of drug delivery systems, holding a total of 3 patents. Her work focuses on developing innovative micelles and nanoparticles that enhance the efficacy of pharmaceutical compounds.
Latest Patents
One of her latest patents involves the creation of polysialic acid-polycaprolactone micelles for drug delivery. These micelles serve as carrier systems for pharmaceutical drugs, such as cyclosporine A (CyA). Physical characterization of the micelles demonstrated favorable properties for drug delivery, including size and zeta potential. In vitro studies confirmed that rheumatoid arthritis synovial fibroblasts can internalize the CyA-loaded micelles. Upon uptake, CyA is released from the PSA-PCL micelle and partitions into the phospholipid membrane. Additionally, the PSA-PCL micelles have shown improved therapeutic efficacy in delivering statins and disease-modifying anti-rheumatic drugs (DMARDs).
Another notable patent by Bader is the development of polysialic acid-based N-trimethyl chitosan gel nanoparticles for systemic drug delivery. These gel nanoparticles are designed to encapsulate and deliver pharmaceutical compounds to patients. They are formed from N-trimethyl chitosan and polysialic acid, preferably in the presence of sodium tripolyphosphate. The optimal ratio of polysialic acid to N-trimethyl chitosan produces nanoparticles with a diameter of approximately 100 nm and a zeta potential above 30 millivolts, ensuring stability for containing pharmaceutical compounds like methotrexate.
Career Highlights
Rebecca A. Bader is affiliated with Syracuse University, where she continues her research and development in drug delivery systems. Her innovative work has positioned her as a key figure in the field, contributing to advancements that have the potential to improve patient outcomes.
Collaborations
Bader collaborates with esteemed colleagues, including Julie M. Hasenwinkel and Jeremy L. Gilbert. Their combined expertise enhances the research efforts at Syracuse University, fostering an environment of innovation and discovery.
Conclusion
Rebecca A. Bader's contributions to drug delivery systems through her innovative patents highlight her role as a leading inventor in the field. Her work not only advances scientific knowledge but
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile