The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 26, 2013
Filed:
Apr. 21, 2010
Julie M. Hasenwinkel, Manlius, NY (US);
Jeremy L. Gilbert, Fayetteville, NY (US);
Danieli C. Rodrigues, Syracuse, NY (US);
Rebecca Bader, Syracuse, NY (US);
Julie M. Hasenwinkel, Manlius, NY (US);
Jeremy L. Gilbert, Fayetteville, NY (US);
Danieli C. Rodrigues, Syracuse, NY (US);
Rebecca Bader, Syracuse, NY (US);
Syracuse University, Syracuse, NY (US);
Abstract
The present invention relates to bone cements and, more particularly, to acrylic-based orthopedic bone cements, their use in spinal applications, and methods for making the same. An embodiment of the present invention provides a method of grafting PMMA brushes on cross-linked PMMA nanospheres comprising at least one of the following steps: performing a hydrolysis reaction of surface methyl ester groups of said cross-linked PMMA nanospheres to form surface carboxylic acid groups of said cross-linked PMMA nanospheres; forming a 2-aminoethyl acrylate compound; coupling said surface carboxylic acid groups of said cross-linked PMMA nanospheres with said 2-aminoethyl acrylate compound to form a coupled compound with an initiating site; and grafting said PMMA brushes onto said initiating site. Another embodiment of the present invention includes an orthopedic bone cement including cross-linked PMMA nanospheres comprising PMMA brushes prepared by this method, and a monomer, wherein polymer to monomer ratio is between about 1:1 and 1.3:1.