logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9241913 B1

PDFFull Text
Date of Patent:
Jan. 26, 2016

Filed:

May. 18, 2012

Polysialic acid-based n-trimethyl chitosan gel nanoparticles for systemic drug delivery

Applicant:

Rebecca A. Bader, Syracuse, NY (US);

Inventor:

Rebecca A. Bader, Syracuse, NY (US);

Assignee:

Syracuse University, Syracuse, NY (US);

Attorneys:

David L. Nocilly

George R. McGuire

Bond Schoeneck & King, PLLC

Primary Examiner:

Suzanne Ziska

Assistant Examiner:

Ivan Greene

Int. Cl.
CPC ...
A61K 31/726 (2006.01); A61K 9/51 (2006.01); A61K 31/519 (2006.01); B82Y 30/00 (2011.01);
U.S. Cl.
CPC ...
A61K 9/5161 (2013.01); A61K 31/519 (2013.01); B82Y 30/00 (2013.01);
Abstract

Gel nanoparticles for encapsulating and delivering a pharmaceutical compound to a patient. The nanoparticles are formed from N-trimethyl chitosan and polysialic acid, preferably in the presence of sodium tripolyphosphate. A ratio of polysialic acid to N-trimethyl chitosan of about 0.5 to 1 produces nanoparticles having diameter of about 100 nm (plus or minus 25 nm) and a zeta potential above 30 milivolts that can stability contain a pharmaceutical compound, such as methotrexate, for delivery to a patient.

Find Patent Forward Citations

Bader, Rebecca. (2016). Polysialic acid-based n-trimethyl chitosan gel nanoparticles for systemic drug delivery (U.S. Patent No. 9241913). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9241913

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…