Location History:
- Arlington, MA (US) (1995 - 1998)
- Bedford, MA (US) (2010)
Company Filing History:
7 out of 8,369 
4 out of 902 
1 out of 1,036 
Years Active: 1995-2010
Title: The Innovations of Ramnath Sasisekharan
Introduction
Ramnath Sasisekharan is a prominent inventor based in Arlington, MA (US). He has made significant contributions to the field of biochemistry, particularly in the study and purification of heparinases. With a total of 7 patents to his name, Sasisekharan's work has advanced our understanding of these important enzymes.
Latest Patents
One of his latest patents is focused on the purification, composition, and specificity of Heparinase I, II, and III from Flavobacterium heparinum. This patent discloses a single, reproducible scheme to simultaneously purify all three heparin lyases from F. heparinum to apparent homogeneity. The kinetic properties of the heparin lyases have been determined, along with the conditions to optimize their activity and stability. Additionally, monoclonal antibodies to the three heparinases are described, which are useful for detection, isolation, and characterization of the heparinases. Another significant patent involves the purification of Heparinase I, II, and III from Flavobacterium heparinum. In this patent, purified heparinases free of lyase activity are produced, each having specific molecular weights of 42,800, 84,100, and 70,800, respectively. The kinetic properties of these heparinases have also been characterized.
Career Highlights
Throughout his career, Ramnath Sasisekharan has worked with prestigious institutions such as the Massachusetts Institute of Technology and the University of Iowa Research Foundation. His research has had a profound impact on the field of enzymology and biochemistry.
Collaborations
Sasisekharan has collaborated with notable figures in the scientific community, including Robert Samuel Langer and Charles L. Cooney. These collaborations have further enriched his research and contributions to the field.
Conclusion
Ramnath Sasisekharan's innovative work in the purification and characterization of heparinases has established him as a key figure in biochemistry. His patents and collaborations reflect his dedication to advancing scientific knowledge and technology.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.