Location History:
- New York, NY (US) (1999 - 2005)
- Baltimore, MD (US) (2000 - 2023)
Company Filing History:
6 out of 3,685 
4 out of 712 
2 out of 1,991 
Years Active: 1999-2023
Title: Innovations and Contributions of Philip A. Cole
Introduction
Philip A. Cole is a distinguished inventor based in Baltimore, MD (US), known for his significant contributions to the field of biochemistry and pharmacology. With a total of 12 patents, he has made remarkable strides in developing compounds that target critical biological pathways.
Latest Patents
Among his latest patents, Cole has developed inhibitors of histone lysine specific demethylase (LSD1) and histone deacetylases (HDACs). This series of phenelzine analogs comprises a phenelzine scaffold linked to an aromatic moiety, demonstrating potency and selectivity for LSD1 versus MAO and LSD2 enzymes. These compounds exhibit significant anti-proliferative activity in various cancer cell lines and provide neuroprotection against oxidative stress. Additionally, he has created methods and compositions for modulating P300/CBP activity, identifying compounds that can influence the activity of p300/CBP, which are crucial for treating diseases associated with these pathways.
Career Highlights
Philip A. Cole has had a notable career, working with prestigious institutions such as The Johns Hopkins University and The Rockefeller University. His research has focused on understanding the molecular mechanisms underlying various diseases, particularly in cancer and neurodegenerative disorders.
Collaborations
Throughout his career, Cole has collaborated with esteemed colleagues, including Erin M. Bowers and Ann Boriack-Sjodin. These partnerships have furthered his research and contributed to the advancement of therapeutic strategies in his field.
Conclusion
Philip A. Cole's innovative work and numerous patents reflect his dedication to advancing medical science. His contributions have the potential to lead to significant breakthroughs in the treatment of various diseases.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.