The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2014
Filed:
Sep. 18, 2009
Applicants:
Philip A. Cole, Baltimore, MD (US);
Bradley P. Barnett, Baltimore, MD (US);
Yousang Hwang, Baltimore, MD (US);
Jef D. Boeke, Baltimore, MD (US);
Inventors:
Philip A. Cole, Baltimore, MD (US);
Bradley P. Barnett, Baltimore, MD (US);
Yousang Hwang, Baltimore, MD (US);
Jef D. Boeke, Baltimore, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 3/04 (2006.01); A61K 38/28 (2006.01); A61P 3/10 (2006.01); A61P 7/12 (2006.01); A61K 38/08 (2006.01); A61K 38/10 (2006.01); A61K 38/16 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); A61K 38/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides inhibitors of ghrelin O-acyltransferase, and methods of making and using them. In some embodiments, the invention provides bisubstrate analog inhibitors of ghrelin O-acyltransferase, which can be effective in treating, for example, obesity and diabetes mellitus.