Location History:
- Germantown, MD (US) (2003)
- Olney, MD (US) (1998 - 2004)
- Gaithersburg, MD (US) (1998 - 2012)
Company Filing History:
10 out of 88 
1 out of 1,521 
1 out of 5,303 
Years Active: 1998-2012
Title: Innovator Profile: Petrus W. Roelvink
Introduction
Petrus W. Roelvink is an accomplished inventor based in Olney, Maryland, known for his significant contributions to the fields of biotechnology and gene therapy. With an impressive portfolio of 12 patents, his work exemplifies the innovative spirit that drives advancements in medical technology.
Latest Patents
Roelvink's latest patents include pioneering developments in gene expression and immunology. One notable invention is the "Minigene expression cassette," which provides methods and compositions for expressing a gene or nucleotide sequence of interest. This invention features an expression cassette that combines a synthetic enhancer, a transthyretin promoter, and a nucleotide sequence, all operably linked. Such an expression cassette is particularly useful in adeno-associated viral (AAV) vectors, including self-complementary AAV vectors, enhancing targeted gene therapies.
Another significant patent is for "Antigenic complexes and methods," which details a complex comprising a virion that recognizes an epitope on an immune effector cell surface, along with a first nucleic acid encoding a non-native antigen. This innovation allows for the effective delivery of these complexes to immune cells, promoting a strong immune response and providing potential immunization from various pathogens. Furthermore, this method can assess the antigenicity of test antigens through the use of a library of such complexes.
Career Highlights
Throughout his career, Petrus W. Roelvink has made substantial strides in the biotechnology sector. He has worked with prominent companies such as GenVec, Inc. and Cornell Research Foundation Inc., where he contributed his expertise in the development of cutting-edge technologies that push the boundaries of science and medicine. His work has not only led to significant patent achievements but also advanced the understanding of gene therapy and immunology.
Collaborations
Collaboration has been a crucial aspect of Roelvink's success. He has partnered with notable professionals, including Thomas J. Wickham and Imre Kovesdi, to enhance research and development in the biotechnology field. These collaborations have fostered innovative approaches and solutions to complex scientific challenges.
Conclusion
Petrus W. Roelvink continues to make an indelible mark on the world of biotechnology with his innovative inventions and numerous patents. His commitment to advancing gene therapy and immunology ensures that he remains a significant figure among contemporary inventors. Roelvink’s contributions not only highlight his inventive prowess but also reflect the potential of biotechnology to transform healthcare and improve lives globally.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.