The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2012

Filed:

Mar. 30, 2007
Applicants:

Mark Kay, Los Altos, CA (US);

Micheal Hebert, Sunnyvale, CA (US);

Petrus Wilhelmus Roelvink, Gaithersburg, MD (US);

David A. Suhy, San Ramon, CA (US);

Inventors:

Mark Kay, Los Altos, CA (US);

Micheal Hebert, Sunnyvale, CA (US);

Petrus Wilhelmus Roelvink, Gaithersburg, MD (US);

David A. Suhy, San Ramon, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods and compositions for expressing a gene or nucleotide sequence of interest are provided. The compositions include an expression cassette that includes a synthetic enhancer, a transthyretin promoter, and a nucleotide sequence operably under the control of the synthetic enhancer and the transthyretin promoter. The expression cassette may be used in an adeno-associated viral (AAV) vector, such as a self-complementary AAV vector.


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