Peter Sebo

Title: The Innovative Contributions of Peter Sebo

Introduction

Peter Sebo is a prominent inventor based in Prague, Czech Republic. He has made significant contributions to the field of immunology through his innovative research and development of polypeptides. With a total of 10 patents to his name, Sebo's work focuses on enhancing the delivery of immunogenic molecules into cells.

Latest Patents

One of his latest patents involves mutant CyaA polypeptides and polypeptide derivatives that are suitable for delivering immunogenic molecules into a cell. This invention relates to mutant CyaA/E570Q+K860 polypeptides, which serve as proteinaceous vectors for delivering molecules of interest into cells expressing the CD11b receptor. The polypeptides derived from the adenylate cyclase protein (CyaA) are designed to retain the binding activity of native CyaA while reducing or suppressing its pore-forming activity compared to the native CyaA toxin. The polypeptides maintain a high sequence identity with specific sequences, ensuring their effectiveness in eliciting an immune response.

Career Highlights

Throughout his career, Peter Sebo has worked with esteemed institutions such as the Institut Pasteur and the Institute of Microbiology of the ASCR, v.v.i. His research has significantly advanced the understanding of immunogenic delivery systems, making him a key figure in his field.

Collaborations

Sebo has collaborated with notable scientists, including Claude Leclerc and Daniel Ladant, further enhancing the impact of his research through shared expertise and knowledge.

Conclusion

Peter Sebo's innovative work in the development of mutant CyaA polypeptides has the potential to revolutionize immunogenic delivery systems. His contributions to the field of immunology are invaluable and continue to inspire future research and development.