The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2011
Filed:
Mar. 05, 2007
Claude Leclerc, Paris, FR;
Mohammed El-azami El-idrissi, Maroc, MA;
Daniel Ladant, Cachan, FR;
Cécile Bauche, Paris, FR;
Peter Sebo, Prague, CZ;
Jirina Loucka, Kladno, CZ;
Radim Osicka, Prague, CZ;
Claude Leclerc, Paris, FR;
Mohammed El-Azami El-Idrissi, Maroc, MA;
Daniel Ladant, Cachan, FR;
Cécile Bauche, Paris, FR;
Peter Sebo, Prague, CZ;
Jirina Loucka, Kladno, CZ;
Radim Osicka, Prague, CZ;
Institut Pasteur, Paris, FR;
Centre National de la Recherche Scientique, Paris, FR;
Abstract
The invention relates to modifiedadenylate cyclase toxins which are deficient for CD11b/CD18 binding and to their use in the preparation of pharmaceutical composition for the treatment of whooping cough and/or for the protection againstinfection. The invention also relates to specific fragments ofadenylate cyclase comprising the CD11b/CD18 interaction domain and their use, especially for targeting a molecule of interest to CD11b expressing cells.