Company Filing History:
7 out of 28 
4 out of 932 
Years Active: 1999-2011
Title: Innovations of Peter Scherrer in Lipid-Encapsulated Nucleic Acid Technologies
Introduction
Peter Scherrer is a notable inventor based in Vancouver, Canada, recognized for his significant contributions to the field of lipid-encapsulated nucleic acid technologies. With a total of 11 patents to his name, Scherrer's work focuses on enhancing the delivery mechanisms of therapeutic agents, particularly in gene transfer applications.
Latest Patents
Among his latest patents, Scherrer has developed methods for the preparation of lipid-nucleic acid compositions. These methods involve combining a mixture of lipids, including protonatable or deprotonatable lipids, with a buffered aqueous solution of charged therapeutic agents, such as polyanionic nucleic acids. This innovative approach results in particles where the therapeutic agent is encapsulated within lipid vesicles. The surface charges on these lipid particles are partially neutralized, leading to compositions with high ratios of therapeutic agents to lipids and encapsulation efficiencies exceeding 50%. Additionally, he has created novel lipid-nucleic acid particulate complexes that are effective for in vitro or in vivo gene transfer. These complexes can be formed using detergent dialysis methods or organic solvents, ensuring that the nucleic acid remains stable and protected from degradation.
Career Highlights
Scherrer's career includes significant roles at Inex Pharmaceuticals Corporation and the University of British Columbia. His work at these institutions has allowed him to advance his research and contribute to the development of innovative therapeutic solutions.
Collaborations
Throughout his career, Scherrer has collaborated with esteemed colleagues, including Michael J. Hope and Pieter Rutter Cullis. These partnerships have further enriched his research and innovation in the field.
Conclusion
Peter Scherrer stands out as a prominent inventor whose work in lipid-encapsulated nucleic acid technologies has the potential to revolutionize gene therapy. His innovative methods and collaborative efforts continue to push the boundaries of scientific research and therapeutic applications.
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