Location History:
- South San Francisco, CA (US) (2015)
- West Chester, PA (US) (2010 - 2016)
- West Point, PA (US) (2016)
Company Filing History:
6 out of 2,405 
5 out of 2,112 
3 out of 8 
Years Active: 2010-2016
Introduction
Paul J Shughrue is an accomplished inventor located in West Chester, Pennsylvania, with a noteworthy portfolio comprising nine patents. His groundbreaking innovations primarily focus on advancing methods and treatments related to Alzheimer's disease, demonstrating his commitment to improving patient outcomes.
Latest Patents
One of Shughrue's latest patents is titled "Method for treating a disease associated with soluble, oligomeric species of amyloid beta 1-42." This invention outlines a method and kit aimed at treating diseases related to the accumulation of soluble oligomer amyloid beta 1-42. The technique employs an antibody or antibody fragment that exhibits a higher affinity for these oligomers compared to other forms of amyloid beta, enhancing therapeutic efficacy.
Another significant patent is "Anti-ADDL monoclonal antibody and uses thereof." This invention focuses on antibodies designed to bind to amyloid β-derived diffusible ligands (ADDLs). These antibodies are selective for ADDLs, possess the ability to penetrate the brain, and serve crucial roles in detecting and diagnosing Alzheimer's disease. Furthermore, they prevent the binding of ADDLs to neurons and inhibit tau phosphorylation, making them beneficial in the treatment of related diseases.
Career Highlights
Throughout his career, Paul J Shughrue has held prominent positions in reputable organizations like Merck Sharp & Dohme Corporation and Northwestern University. His experience in these esteemed institutions has contributed significantly to his innovative work and the development of effective treatments for Alzheimer's disease.
Collaborations
In his journey of innovation, Paul J Shughrue has collaborated with notable coworkers such as Paul Acton and Zhiqiang An. These partnerships have enriched his research efforts and expanded the scope of his inventive contributions, ultimately aiding in the fight against neurological diseases.
Conclusion
Paul J Shughrue stands out as a prominent inventor in the realm of Alzheimer's disease research. With his dedication to innovation, demonstrated through his nine patents, Shughrue continues to make significant strides in developing treatments that may transform the lives of those affected by Alzheimer's. His work not only showcases his inventiveness but also his unwavering commitment to advancing medical science for the betterment of society.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.