The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2016
Filed:
Dec. 04, 2012
Acumen Pharmaceuticals, Inc., Livermore, CA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
William F. Goure, Livermore, CA (US);
Franz F. Hefti, Livermore, CA (US);
Renee C. Gaspar, West Point, PA (US);
Paul J. Shughrue, West Chester, PA (US);
Fubao Wang, Dresher, PA (US);
Weirong Wang, West Point, PA (US);
Ningyan Zhang, West Point, PA (US);
Wei-Qin Zhao, North Wales, PA (US);
Alexander McCampbell, Cambridge, MA (US);
Min Xu, Ambler, PA (US);
Acumen Pharmaceuticals, Inc., Livermore, CA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
This invention is a method and kit for treating a disease associated with, or resulting from, the accumulation of soluble oligomer amyloid beta 1-42 using an antibody, or antibody fragment thereof, that has a higher affinity for amyloid beta 1-42 oligomers than for amyloid beta 1-42 monomer, amyloid beta 1-40 monomer, plaques and amyloid beta fibrils and, optionally, a tau therapeutic or an inhibitor of amyloid beta production or aggregation.