Ambler, PA, United States of America

Min Xu

USPTO Granted Patents = 4 

 

 

Average Co-Inventor Count = 9.4

ph-index = 1

Forward Citations = 23(Granted Patents)


Company Filing History:


Years Active: 2007-2016

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4 patents (USPTO):Explore Patents

Title: Inventor Min Xu: Pioneering Treatments for Alzheimer’s Disease

Introduction

Min Xu, an accomplished inventor based in Ambler, PA, has made significant contributions to the field of biomedical innovations. With a remarkable portfolio of four patents, his work primarily revolves around methods for treating diseases associated with amyloid beta, particularly related to Alzheimer’s disease.

Latest Patents

One of Min Xu's notable patents is the "Method for treating a disease associated with soluble, oligomeric species of amyloid beta 1-42." This innovative method involves a kit designed to treat conditions linked to the accumulation of soluble oligomer amyloid beta 1-42. The invention utilizes an antibody or an antibody fragment that exhibits a higher affinity for amyloid beta 1-42 oligomers than for its monomeric forms and other amyloid structures, potentially combined with tau therapeutics or inhibitors of amyloid beta production or aggregation.

Another significant patent is the "Anti-ADDL monoclonal antibody and uses thereof." This invention focuses on antibodies that specifically bind to amyloid β-derived diffusible ligands (ADDLs). These antibodies are designed to penetrate the blood-brain barrier, aiding in the detection and diagnosis of Alzheimer's disease. Additionally, they prevent ADDLs from binding to neurons, hinder their assembly, and inhibit tau phosphorylation, making them valuable in therapeutic methods for diseases associated with these ligands.

Career Highlights

Min Xu has garnered extensive experience through his work with prominent companies, such as Merck Sharp & Dohme Corporation and Acumen Pharmaceuticals, Inc. His roles in these organizations have enabled him to transform scientific knowledge into practical applications that address critical health challenges.

Collaborations

Throughout his career, Min Xu has collaborated with notable professionals, including Renee C. Gaspar and Paul J. Shughrue. These partnerships have contributed to the advancement of his research and the development of his innovative treatments, harnessing collective expertise to tackle complex biomedical issues.

Conclusion

Min Xu's inventive spirit and dedication to addressing Alzheimer’s disease illustrate the impact of innovation in the medical field. His patents not only enhance our understanding of amyloid beta's role in neurodegenerative diseases but also pave the way for potential advancements in treatment options for millions affected by Alzheimer's disease. With his ongoing contributions, Min Xu continues to inspire future generations of inventors and researchers.

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