Location History:
- Hopkinton, MA (US) (2015)
- Dresher, PA (US) (2011 - 2016)
- West Point, PA (US) (2016)
Company Filing History:
4 out of 2,405 
3 out of 8 Years Active: 2011-2016
Title: Innovations of Fubao Wang in Alzheimer's Disease Research
Introduction
Fubao Wang, an accomplished inventor based in Dresher, PA, has made significant strides in the field of Alzheimer's disease research. With five patents to his name, his groundbreaking work in the development of therapeutic methods and antibodies showcases his commitment to addressing complex neurological conditions.
Latest Patents
Wang’s latest patents highlight his innovative approaches to treating diseases associated with amyloid beta. One notable invention is his method for treating a disease associated with soluble, oligomeric species of amyloid beta 1-42. This method entails using an antibody or antibody fragment that demonstrates a higher affinity for amyloid beta 1-42 oligomers compared to the monomer forms, enabling targeted therapeutic interventions.
Another significant patent is the Anti-ADDL monoclonal antibody and its uses. This invention focuses on antibodies that selectively bind to amyloid beta-derived diffusible ligands (ADDLs). These antibodies not only have the ability to penetrate the brain but also play a crucial role in diagnosing Alzheimer's disease by detecting ADDLs. Furthermore, they block the binding of ADDLs to neurons, assembly of ADDLs, and inhibit tau phosphorylation, making them invaluable in preventing and treating related diseases.
Career Highlights
Throughout his career, Fubao Wang has worked with prominent organizations, notably Merck Sharp & Dohme Corporation and Acumen Pharmaceuticals, Inc. His tenure at these established companies has provided him with the platform to advance his research and develop his notable patents, significantly contributing to the biomedical field.
Collaborations
Wang's work has also been enriched through collaborations with esteemed colleagues, including Renee C. Gaspar and Paul J. Shughrue. Their combined efforts in research have played a fundamental role in the successful development of new therapeutic methods aimed at combating Alzheimer's disease.
Conclusion
Fubao Wang’s contributions to the understanding and treatment of Alzheimer’s disease through his innovative patents underline the impact of dedicated research in the field of neurology. As the fight against neurodegenerative diseases progresses, inventors like Wang continue to pave the way for the development of effective therapies, offering hope for better diagnosis and treatment options in the future.