Osamu Nureki

This inventor holds 14 USPTO granted patents and 6 published patent applications and 1 EPO patent. Top assignees: The University of Tokyo, Massachusetts Institute of Technology, The Broad Institute, Inc.. Active years: 2009-2026.

USPTO Granted Patents = 14 (Patent Applications = 6)

% Patents Active = 78.6

EPO Patents = 1 (Patent Applications = 9)

Average Co-Inventor Count = 5.9

ph-index = 3

Forward Citations = 25(Granted Patents)

Location History:

Bunkyo-ku, JP (2022)
Kanagawa, JP (2009 - 2023)
Tokyo, JP (2019 - 2023)
Yokohama, JP (2023)

Company Filing History:

12 out of 1,352

The University of Tokyo

patents

6 out of 8,576

Massachusetts Institute of Technology

patents

6 out of 482

The Broad Institute, Inc.

Modalis Therapeutics Corporation

Shionogi Company Limited

Japan Science and Technology Agency

patents

10. 1 out of 229

Mochida Pharmaceutical Co., Ltd.

patents

where one patent can have more than one assignee

Years Active: 2009-2026

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14 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12522859 - METHOD AND KIT FOR DETECTING TARGET NUCLEIC ACID FRAGMENT (2026-01-13),

2. 12258595 - Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems (2025-03-25),

3. 12168789 - Engineering and optimization of systems, methods, enzymes and guide scaffolds of CAS9 orthologs and variants for sequence manipulation (2024-12-17),

4. 12152259 - Modified CAS9 protein, and use thereof (2024-11-26),

5. 11702645 - Polynucleotide encoding modified CAS9 protein (2023-07-18),

6. 11597919 - Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems (2023-03-07),

7. 11578312 - Engineering and optimization of systems, methods, enzymes and guide scaffolds of CAS9 orthologs and variants for sequence manipulation (2023-02-14),

8. 11530396 - Modified CAS9 protein, and use thereof (2022-12-20),

9. 11371030 - Modified Cas9 protein and use thereof (2022-06-28),

10. 11155795 - CRISPR-Cas systems, crystal structure and uses thereof (2021-10-26),

11. 10550372 - Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems (2020-02-04),

12. 10189843 - Fused pyrazole derivative having autotaxin inhibitory activity (2019-01-29),

13. 10183949 - Pyrimidinone derivative having autotaxin-inhibitory activity (2019-01-22),

14. 7514240 - EGR-EGFR complex (2009-04-07),

Title: Osamu Nureki: Innovator in CRISPR Technology

Introduction

Osamu Nureki is a prominent inventor based in Tokyo, Japan. He has made significant contributions to the field of molecular biology, particularly in the development of CRISPR technology. With a total of 14 patents, Nureki's work has advanced our understanding and application of gene editing techniques.

Latest Patents

Nureki's latest patents include a "Method and Kit for Detecting Target Nucleic Acid Fragment" and "Systems, Methods and Compositions for Sequence Manipulation with Optimized Functional CRISPR-Cas Systems." These inventions provide innovative systems and methods for altering the expression of target gene sequences and related gene products. His work offers structural information on the Cas protein of the CRISPR-Cas system, which is crucial for generating modified components of the CRISPR complex. Additionally, he has developed methods for directing CRISPR complex formation in eukaryotic cells, showcasing the versatility and potential of CRISPR technology.

Career Highlights

Throughout his career, Nureki has been associated with prestigious institutions such as The University of Tokyo and the Broad Institute, Inc. His research has not only contributed to academic knowledge but has also paved the way for practical applications in genetic engineering.

Collaborations

Nureki has collaborated with notable scientists, including Hiroshi Nishimasu and Ryuichiro Ishitani. These partnerships have enhanced the scope and impact of his research, leading to groundbreaking advancements in the field.

Conclusion

Osamu Nureki's innovative work in CRISPR technology exemplifies the potential of modern science to transform genetic research and applications. His contributions continue to influence the landscape of molecular biology and gene editing.